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. 2018 Mar 7;19:39. doi: 10.1186/s12881-018-0544-6

Table 3.

OR and CI for TCM patients and controls with CAD being heterozygote and homozygote for minor allele in the ADRB1 (G), GRK5 (T) and BAG3 (C) gene

Polymorphism TCM OR (CI) CAD Controls OR (CI)
Heterozygote for minor allele
 β1AR 1.07 (0.75–1.55) 0.99 (0.65–1.50)
 BAG3 1.27 (0.74–2.19) 1.71 (0.88–3.32)
 GRK5 0.45 (0.11–1.85) 1.22 (0.37–4.07)
Homozygote for minor allele
 β1AR 0.95 (0.47–1.93) 1.18 (0.55–2.52)
 BAG3 0.79 (0.46–1.35) 0.59 (0.3–1.14)

Abbreviations: TCM Takotsubo cardiomyopathy; CAD coronary artery disease; ADRB1 = β1-adrenergic receptor; GRK5 G-protein-coupled receptor kinase 5; BAG3 Bcl-associated athanogene 3