Fig. 1.

Comparison of XDP versus control tractography for a priori comparisons. Total termination tractography counts are shown for the striosome-weighted and matrix-weighted regions for the caudate (A,C) and putamen (B,D). XDP values are shown in red and control values in blue. Error bars indicate standard error of the mean. XDP: X-linked dystonia-parkinsonism. Images (from fslview) below graphs show representative sections through the left and right hemisphere averaged healthy control tractography for each of the four a priori tractography measures, superimposed on the MNI152_T1_1mm template. Note that these images are intended (and thresholded) to be qualitative only, and are included simply to illustrate the territory covered most prominently by each of the four measures; they do not convey information about magnitude or spatial extent. The MNI coordinate indicates the location of each image slice. Images are in radiologic format; L: left hemisphere and R: right hemisphere. *significant at p < 0.005; ^†trend toward significance (within an order of magnitude of the significance p threshold).