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. 2017 Oct 28;17:835–846. doi: 10.1016/j.nicl.2017.10.025

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© 2017 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 4 — Comparison of tractography measures for posthoc comparisons in the 17 XDP versus 17 controls cohort, as compared with the 10 XDP versus 10 controls cohort. Total termination tractography counts from Fig. 1 (17 XDP versus 17 controls, top row) are compared with values for the smaller, more tightly matched cohort (bottom row). Individual striosome-weighted regions were individually assessed for connectivity with the ipsilateral putamen: (A) Left anterior insula, (B) Right anterior insula, (C) Left anterior/subcallosal cingulate, (D) Right anterior/subcallosal cingulate, (E) Left orbitofrontal cortex, (F) Right orbitofrontal cortex. Error bars indicate standard error of the mean. *significant at p < 0.005; ^†trend toward significance (within an order of magnitude of the significance p threshold); ^†* trend without ICV correction, but significant at p < 0.005 when ICV corrected. XDP: X-linked dystonia-parkinsonism. ant ins: anterior insula; ant cing: anterior/subcallosal cingulate; OFC: orbitofrontal cortex.