TABLE 3.

Multistate Survival Analysis: Estimated Incidence of Sz and Remaining Chance of Sz

		Remaining Probability of Sz
Clinical Factors	State	1 Hour	6 Hours	12 Hours	24 Hours	Hours to < 5% Sz	Overall Probability of Sz
No coma & No prior Sz,	Entry	0.04 (0.03–0.06)	0.02 (0.01–0.03)	0.02 (0.01–0.03)	0.01 (0.00–0.02)	0.4	Sz from entry state	0.09 (0.06–0.12)
n = 312 [101]a	EEG risk	0.15 (0.10–0.20)	0.08 (0.05–0.12)	0.06 (0.04–0.09)	0.02 (0.01–0.06)	14.4	Sz from risk state	0.18 (0.12–0.24)
							Enter risk state	0.33 (0.29–0.40)
No coma & prior Sz,	Entry	0.12 (0.10–0.17)	0.07 (0.05–0.11)	0.05 (0.04–0.09)	0.02 (0.01–0.05)	12.7	Sz from entry state	0.30 (0.23–0.37)
n = 223 [91]a	EEG risk	0.28 (0.21–0.37)	0.15 (0.10–0.24)	0.12 (0.08–0.19)	0.04 (0.02–0.12)	21.7	Sz from risk state	0.35 (0.25–0.48)
							Enter risk state	0.40 (0.21–0.50)
Comatose & no prior Sz,	Entry	0.05 (0.03–0.08)	0.03 (0.01–0.05)	0.02 (0.01–0.04)	0.01 (0.00–0.02)	1.2	Sz from entry state	0.13 (0.08–0.17)
n = 85 [34]a	EEG risk	0.33 (0.23–0.47)	0.18 (0.11–0.29)	0.14 (0.09–0.24)	0.05 (0.02–0.14)	16.7	Sz from risk state	0.39 (0.28–0.52)
							Enter risk state	0.36 (0.26–0.48)
Comatose & prior Sz,	Entry	0.16 (0.10–0.24)	0.09 (0.05–0.14)	0.07 (0.04–0.12)	0.02 (0.01–0.07)	16.4	Sz from entry state	0.36 (0.24–0.50)
n = 44 [19]a	EEG risk	0.57 (0.41–0.74)	0.34 (0.22–0.52)	0.26 (0.17–0.43)	0.10 (0.04–0.28)	44.2	Sz from risk state	0.64 (0.48–0.86)
							Enter risk state	0.42 (0.29–0.58)

Data are presented numbers in parentheses representing 95% confidence intervals from bootstrap resampling. EEG risk state in this context refers to subjects who develop the EEG findings of lateralized periodic discharges, bilateral periodic discharges, lateralized rhythmic discharges, lateralized spike wave, sporadic epileptiform discharges, and/or brief ictal rhythmic discharges.

^aNumber of subjects in each category in brackets is the number who developed an EEG risk factor.

EEG = electroencephalographic; Sz = seizures.