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. 2018 Feb 22;2018:7040498. doi: 10.1155/2018/7040498

Table 2.

Summary of time-kill log-fold changes in CFU at 72 h.

Species Strain Suscept. to FLU (S/R) Drug Log-fold change in CFU at each drug conc.
(μg/ml)
2 8 32 128
C. albicans ATCC 44858 S RZF ++ ++++ ++++ ++++
TER - - + +
DPL001 R RZF ++++ ++++ ++++ ++++
TER - - - -
R357 R RZF + ++ +++ ++++
TER - - - -

C. glabrata CG01 S RZF + ++++ ++++ ++++
TER - - - -
ATCC 200918 R RZF - +++ +++ ++++
TER - - - -
MMX 7070 R RZF +++ +++ ++ +++
TER - - - -

C. tropicalis CT02 S RZF - ++ +++ +++
TER - - - +
MMX 7255 R RZF ++ + ++ ++
TER - - - -
MMX 7525 R RZF +++ ++++ +++ +++
TER - - - -

C. parapsilosis CP02 S RZF + ++ ++ +++
TER - - ++ ++
CP01 R RZF - ++ ++ ++
TER - - - -
MMX 7370 R RZF - + + ++
TER - - - -

C. krusei ATCC 6258 R RZF ++++ ++++ ++++ ++++
TER - - + ++++
ATCC 14243 R RZF ++++ ++++ ++++ ++++
TER - - - ++++

Symbols denote log-fold changes in CFU from starting inoculum: increase or <1-log reduction (-); ≥1- to <2-fold reduction (+); ≥2- to <3-fold reduction in CFU (++); ≥3- to <4-fold reduction in CFU (+++); ≥4- to <5-fold reduction in CFU (++++). indicates fungicidal activity (≥3-log CFU reduction).