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Full factorial ANOVA across the whole-brain whole-range degree centrality network showed a significant interaction effect of genotype × diagnosis at the PCU (Panel A, the maximal peak voxel MNI coordinates: x, y, z = [9–69 63]). Further analysis found that the interaction effect was limited to short-range connections (Panel C). Separate analyses for patients and controls found that these effects were specific to patients (Panel B for whole-range, Panel D for short-range).
