Table 4.

Adjusted BREAST-Q patient-reported outcomes by treatment group

	Psychosocial well-being* (n = 455†)			Sexual well-being‡ (n = 198†)			Physical well-being§ (n = 453†)			Adverse radiation effects‖ (n = 201†)
	n	Mean (95% CI)	P value	n	Mean (95% CI)	P value	n	Mean (95% CI)	P value	n	Mean (95% CI)	P value
Lump + WBI	103	75.9 (69.8–82.0)	Referent	41	49.1 (41.4–56.7)	Referent	104	81.4 (78.2–84.6)	Referent	103	90.4 (86.7–94.1)	Referent
Lump + Brachy	99	78.3 (72.7–83.9)	.40	41	55.1 (43.7–66.5)	.30	97	86.9 (83.4–90.5)	.02	98	94.8 (90.2–99.5)	.04
Lump alone	74	75.8 (69.8–81.8)	.97	30	53.2 (42.3–64.1)	.49	74	79.7 (74.8–84.5)	.55	–	–	–
Mast alone	81	69.9 (63.6–76.2)	.06	36	40.4 (29.4–51.4)	.17	82	81.6 (77.5–85.6)	.94	–	–	–
Mast + RT	98	64.3 (57.7–71.0)	<.001	50	27.2 (16.4–38.0)	<.001	96	73.0 (69.2–76.7)	<.001	–	–	–

Abbreviations: CI = confidence interval; Lump alone = lumpectomy plus endocrine therapy alone; Lump + Brachy = lumpectomy plus brachytherapy; Lump + WBI = lumpectomy plus whole-breast irradiation; Mast alone = mastectomy alone; Mast + RT = mastectomy plus radiation therapy.

^*The model for BREAST-Q psychosocial well-being was adjusted for Charlson Comorbidity Index and axillary surgery.

^†For each section, patients were included if they had ≥50% nonmissing responses in that section; missing responses were assigned a value based on the mean of the nonmissing responses (in accordance with BREAST-Q scoring tables).

^‡The model for BREAST-Q sexual well-being was adjusted for Charlson Comorbidity Index, axillary surgery, and geographic region.

^§The model for BREAST-Q physical well-being was adjusted for age, bra cup size, and geographic region.

^‖The model for BREAST-Q adverse radiation effects was adjusted for race and bra cup size.