. Author manuscript; available in PMC: 2019 Apr 15.

Published in final edited form as: Int J Cardiol. 2018 Apr 15;257:318–323. doi: 10.1016/j.ijcard.2017.10.121

Table 3.

Multivariate Logistic Regression Analysis Relating Severe OSA (AHI ≥30, outcome) to heart rate/HRV measures (n=1,298)

	OR	95% CI lower, upper	P-value

HRV (time domain)

Mean heart rate (bpm)	1.023	1.004, 1.043	0.019
SDNN (ms)	1.008	1.003, 1.013	0.002
rMSSD (ms)	1.003	0.999, 1.006	0.189
pNN20, %	0.999	0.990, 1.007	0.734
pNN50, %	1.000	0.989, 1.012	0.984

HRV (frequency domain)

LF nu	5.210	1.433, 18.942	0.012
LF (ms²)	1.000	0.999, 1.000	0.126
HF nu	0.192	0.053, 0.698	0.012
HF (ms²)	1.000	0.999, 1.000	0.301
LF/HF ratio	1.083	0.996, 1.177	0.062

Analysis adjusted by age, sex, race/ethnicity, smoking status; BMI; HTN, DM, bb, and any ccb. OSA= obstructive sleep apnea; OR= odds ratio; CI= confidence interval; HRV= heart rate variability; NN= normal-to-normal intervals; SDNN= the standard deviation of NN intervals; rMSSD= the square root of the mean of the squares of the successive differences between adjacent NN intervals; pNN20= the percentage of absolute differences in successive NN values >20ms; pNN50= the percentage of absolute differences in successive NN values >50ms; LF= low frequency power (between 0.04 to 0.15 Hz); HF= high frequency power (between 0.15 to 0.4 Hz); nu= normalized units; ms= milliseconds. BMI= body mass index; HTN= hypertension; DM= Diabetes Mellitus, bb= beta-blocker; ccb= calcium channel blocker;