Skip to main content
. 2018 Feb 4;10(2):178–196. doi: 10.18632/aging.101375

Table 2. Association analysis of selected SNPs with Type 2 Diabetes.

Gene SNP ID Major/Minor allele MAF OR (95% CI)a P-value
ADIPOQ rs266729 C/G 0.239 1.08 (0.83-1.42) 0.555
ADIPOQ-AS1 rs1063539 G/C 0.111 1.03 (0.71-1.48) 0.889
APOE rs440446 G/C 0.375 1.16 (0.91-1.48) 0.224
CAT rs1001179 G/A 0.214 0.93 (0.7-1.24) 0.629
CLPTM1L rs401681 C/T 0.40 1.09 (0.86-1.39) 0.467
DDAH1 rs13373844 A/C 0.334 1.09 (0.85-1.40) 0.496
DDAH1 rs7521189 A/G 0.466 0.98 (0.60-1.57) 0.840
EPO rs1617640 T/G 0.330 1.08 (0.84-1.39) 0.544
EPO rs507392 T/C 0.334 1.13 (0.88-1.46) 0.339
EPO rs551238 A/C 0.329 1.1 (0.86-1.42) 0.435
FTO rs1121980 C/T 0.477 1.01 (0.8-1.27) 0.928
FTO rs1421085 T/C 0.464 1.01 (0.8-1.27) 0.933
FTO rs17817449 T/G 0.446 1.06 (0.84-1.33) 0.621
FTO rs1800592 A/G 0.249 0.85 (0.65-1.11) 0.221
FTO rs8050136 C/A 0.447 1.02 (0.81-1.29) 0.847
FTO rs9939609 T/A 0.441 1.03 (0.82-1.3) 0.804
HIF1A rs11549465 C/T 0.151 1.08 (0.78-1.49) 0.651
IGF2BP2 rs4402960 G/T 0.347 1.28 (1.01-1.62) 0.038
IRS1 (500 kb downstream) rs2943641 C/T 0.384 1.11 (0.87-1.40) 0.404
KCNJ11 rs5215 T/C 0.341 1.01 (0.79-1.28) 0.963
TCF7L2 rs7903146 C/T 0.405 1.22 (0.96-1.55) 0.097
TERC rs12696304 C/G 0.266 1.06 (0.82-1.36) 0.680
TERT rs2735940 T/C 0.415 1.34 (1.05-1.71) 0.017
TERT rs2736098 G/A 0.303 0.64 (0.49-0.84) 0.001
TERT rs2736109 G/A 0.423 0.79 (0.62-1.01) 0.061
UCP1 rs3811787 T/G 0.255 0.85 (0.65-1.11) 0.225
UCP1 rs45539933 C/T 0.063 0.99 (0.61-1.6) 0.969
UCP2 rs660339 C/T 0.354 0.95 (0.74-1.21) 0.676
UCP3 rs1800849 C/T 0.15 0.87 (0.62-1.21) 0.404
VEGFA rs3025021 C/T 0.349 0.87 (0.67-1.13) 0.285

Abbreviations: MAF, Minor Allele Frequency; OR, odds ratio; CI, confidence interval.

Significant p-values (<0.05) are highlighted in bold.

a For each SNP an adjusted additive model was considered.