Table 1. Characteristics of donors.
| Young | Middle-aged | Old | Subset* | ||||
| (N=10) | (N=80) | (N=10) | (N=52) | ||||
| Female, no.(%) | 7 (70.0) | 40 (50.0) | 6 (60.0) | 25 (48.1) | |||
| Age, years | 22.8 (1.5) | 63.2 (7.3) | 90.2 (0.5) | 64.2 (6.9) | |||
| Member of long-lived family | n/a | 40 (50.0) | n/a | 26 (50.0) | |||
| Body mass index, kg/m2 | 22.2 (1.8)a | 26.2 (4.1)b | 25.4 (3.8) | 25.9 (4.3) | |||
| Co-morbidities | |||||||
| Cerebrovascular accident | 0/10 (0.0) | 3/76 (3.9) | 2/10 (20.0) | 3/51 (5.9) | |||
| Chronic obstructive pulmonary disease | 0/10 (0.0) | 3/75 (4.0) | 1/10 (10.0) | 1/51 (2.0) | |||
| Diabetes mellitus | 0/10 (0.0) | 7/74 (9.5) | 2/10 (20.0) | 4/51 (7.8) | |||
| Hypertension | 0/10 (0.0) | 17/76 (22.4) | 5/10 (50.0) | 15/52 (28.8) | |||
| Malignancies | 0/10 (0.0) | 3/72 (4.2) | 1/10 (10.0) | 1/50 (2.0) | |||
| Myocardial infarction | 0/10 (0.0) | 0/75 (0.0) | 3/10 (30.0) | 1/52 (1.9) | |||
| Rheumatoid arthritis | 0/10 (0.0) | 0/76 (0.0) | 3/10 (30.0) | 0/52 (0.0) | |||
| Smoking, current | 0/10 (0.0) | 10/76 (13.2) | 1/10 (10.0) | 3/48 (6.3) | |||
SD: standard deviation. a: N=8, b: N=77. N/a: not applicable. Data are depicted as either mean (SD) or number (%). Diseases and intoxications are given as no./total known (%). * This subset was used for the correlation between in vitro senescence markers versus in situ p16INK4a positive human fibroblasts (3B).