Figure 2.

Identification of potential Fgf23 enhancers and production of Fgf23 ^−16KO mice. (A) ChIP‐seq tag density (normalized to 10⁷ tags) for histone modifications and CTCF binding across the Fgf23 gene locus in differentiated IDG‐SW3 osteocytes. (B) Schematic describing the deletion of the −16kb region from the mouse genome via CRSIPR‐Cas9 genome editing.