TABLE 2.
Comparison between mean values (and standard deviations) of renal function markers in HIV-infected (n = 30) and uninfected women (n = 30).
| Variable | HIV-infected (TDF exposed) | HIV-uninfected (control) | p-value | Adjusted p-value§ |
|---|---|---|---|---|
| SCr (µmol/L) | 50.0 ± 20.3 | 54.0 ± 12.1 | 0.028†* | 0.441 |
| SrP (mmol/L) | 1.05 ± 0.2 | 0.99 ± 0.16 | 0.204‡ | - |
| Serum urea (mmol/L) | 3.3 ± 1.7 | 3.50 ± 1.32 | 0.507‡ | - |
| Serum uric acid (µmol/L) | 278.7 ± 122 | 311 ± 99.6 | 0.265‡ | - |
| Glucosuria (mmol/L) | 0.12 ± 0.09 | 0.19 ± 0.27 | 0.59† | - |
| UCr (mmol/L) | 4.3 ± 3.1 | 6.0 ± 5.8 | 0.145‡ | - |
| UP (mmol/L) | 5.4 ± 5.3 | 7.5 ± 9.4 | 0.524† | - |
| UNa (mmol/L) | 75.5 ± 55.7 | 101.7 ± 42.3 | 0.048‡* | 0.119 |
| Albuminuria (mg/mmol) | 18.0 ± 78.3 | 8.8 ± 27.9 | 0.028†* | 0.048* |
| TmPO4/GFR | 1.18 ± 0.24 | 1.15 ± 0.27 | 0.645‡ | - |
| eGFR (mL/min/1.73 m2) | 125.8 ± 39.6 | 105.0 ± 25.5 | 0.02‡* | 0.047* |
| CrCl (mL/min) | 112.5 ± 40.5 | 104.9 ± 43.0 | 0.486‡ | 0.048* |
| Urine albumin (mg/L) | 33.9 ± 131.0 | 35.5 ± 112.4 | 0.126† | - |
†
p-value calculated from Mann–Whitney test;
‡
p-value calculated from unpaired t-test;
§
p-value resulting from ANCOVA adjusted for weight.
*
p < 0.05.