TABLE 3.
Doses of antiretrovirals for HIV preferred for post-exposure in adults and adolescents.
| Generic name | Dose |
|---|---|
| Tenofovir (TDF) | 300 mg once daily |
| Lamivudine (3TC) | 150 mg twice daily or 300 mg once daily |
| Emtricitabine (FTC) | 200 mg once daily |
| Stavudine (d4T) | 30 mg twice daily |
| Raltegravir (RAL) | 400 mg twice daily |
| Atazanavir/ritonavir (ATV/r) | 300/100 mg once daily |
| Lopinavir/ritonavir (LPV/r) | 400/100 mg twice daily or 800/200 mg once daily† |
| Darunavir + ritonavir (DRV/r) | 800/100 mg once daily or 600/100 mg twice daily |
| Efavirenz (EFV) | 600 mg at night (400 mg if weight < 40 kg) |
Source: Adapted from World Health Organization. Guidelines on post-exposure prophylaxis for HIV and the use of co-trimoxazole prophylaxis for HIV-related infections among adults, adolescents and children: Recommendations for a public health approach: December 2014 supplement to the 2013 consolidated ARV guidelines. Geneva: World Health Organization; 2014
†, Once-daily dosing can be considered as an alternative for adults, but more data needed for children and adolescents.