Table 2. Expression levels of lipid metabolism gene in the control and the obesity group.
| Gene | Control (n = 39) | Obesity (n = 11) | p |
|---|---|---|---|
| Lipids metabolism | |||
| PPARα | 1.0±0.4 | 0.7±0.3 | <0.05* |
| PPARδ | 1.0±0.5 | 0.6±0.3 | <0.01** |
| Cholesterol metabolism | |||
| HMGCR | 1.0±0.5 | 0.4±0.2 | <0.01** |
| SREBP-2 | 1.0±0.4 | 0.6±0.3 | <0.01** |
| LDLR | 1.0±0.4 | 0.8±0.4 | 0.07 |
| LXRα | 1.0±0.3 | 1.0±0.3 | 0.83 |
| Fatty acids metabolism | |||
| SREBP-1c | 1.0±0.4 | 0.8±0.4 | 0.12 |
| FAS | 1.0±0.6 | 0.6±0.3 | <0.05* |
| ACC-1 | 1.0±0.5 | 0.5±0.2 | <0.01** |
| SCD-1 | 1.0±0.7 | 0.9±0.5 | 0.54 |
| CPT-1α | 1.0±0.4 | 0.8±0.4 | 0.17 |
Expression levels of lipid metabolism-related genes in skin samples of the control group and the obesity group. Data are presented as mean ± SD. Statistical comparisons between the groups are performed by unpaired Student’s t-test (*p<0.05, **p<0.01).