Table 3. Correlation between gene expression and BMI.
| all subjects | BMI <22 | 22 ≦ BMI < 35 | ||||
|---|---|---|---|---|---|---|
| Gene | r | p | r | p | r | p |
| Lipids metabolism | ||||||
| PPARα | 0.003 | 0.98 | -0.363 | 0.20 | -0.154 | 0.37 |
| PPARδ | -0.276 | 0.06 | 0.332 | 0.25 | -0.426 | <0.05* |
| Cholesterol metabolism | ||||||
| HMGCR | -0.183 | 0.20 | 0.305 | 0.29 | -0.602 | <0.01** |
| SREBP-2 | -0.230 | 0.11 | -0.196 | 0.50 | -0.310 | 0.07 |
| LDLR | -0.160 | 0.27 | -0.209 | 0.49 | -0.264 | 0.12 |
| LXRα | 0.039 | 0.79 | -0.705 | <0.01** | 0.010 | 0.95 |
| Fatty acids metabolism | ||||||
| SREBP-1c | -0.017 | 0.91 | -0.068 | 0.82 | -0.065 | 0.71 |
| FAS | -0.097 | 0.52 | 0.020 | 0.95 | -0.204 | 0.26 |
| ACC-1 | -0.045 | 0.75 | 0.336 | 0.24 | -0.559 | <0.01** |
| SCD-1 | 0.294 | <0.05* | 0.200 | 0.49 | -0.027 | 0.88 |
| CPT-1α | -0.180 | 0.22 | -0.349 | 0.22 | -0.148 | 0.40 |
Spearman’s rank correlation coefficients (r) of BMI with the expression levels of lipid metabolism-related genes (*p<0.05, **p < 0.01).