Table 4. Correlation between gene expression and the amounts of each lipid in the skin.
| Cholesterol | Fatty acids | ||||
|---|---|---|---|---|---|
| Gene | r | p | Gene | r | p |
| PPARα | 0.182 | 0.21 | PPARα | 0.110 | 0.45 |
| PPARδ | 0.323 | <0.05* | PPARδ | 0.434 | <0.01** |
| HMGCR | 0.476 | <0.01** | SREBP-1c | -0.053 | 0.72 |
| SREBP-2 | 0.150 | 0.30 | FAS | 0.052 | 0.73 |
| LDLR | 0.045 | 0.76 | ACC-1 | 0.494 | <0.01** |
| LXRα | -0.036 | 0.81 | SCD-1 | 0.053 | 0.72 |
| CPT-1α | -0.105 | 0.47 | |||
Spearman’s rank correlation coefficients (r) for lipid metabolism-related gene expression levels versus lipid levels in skin samples from all subjects (*p<0.05, **p < 0.01).