TABLE 4.
Performance of PIMA™ analysers compared to National Health Laboratory Services at different CD4+ T-cell thresholds.
| CD4+ T-cells/mm3 | Sensitivity (%) | Specificity (%) | Number misclassified | Number misclassified (%) | Correctly classified (%) | FP Rate | FN Rate | Negative predictive value (%) | Positive predictive value (%) |
|---|---|---|---|---|---|---|---|---|---|
| ≤ 200 | 73.50 | 98.40 | 25 | 9.3 | 90.7 | 3/25 | 22/25 | 85.20 | 95.30 |
| ≤ 350 | 83.50 | 92.30 | 35 | 13.0 | 87.0 | 8/35 | 27/35 | 78.10 | 94.50 |
| ≤ 500 | 94.00 | 78.40 | 24 | 9.0 | 91.0 | 11/24 | 13/24 | 75.50 | 94.90 |
Note: PIMA™ point-of-care [POC] testing for CD4 counts in predicting antiretroviral initiation in HIV-infected individuals in KwaZulu-Natal, Durban, South Africa.
FP, false-positive; FN, false-negative.