Table 3.
Baseline and follow-up measurements of glutathione peroxidase and malondialdehyde during study intervention
| Placebo group | NAC group | p -value | |
|---|---|---|---|
| GPX0 (U/g Hg), Mean ± SD Median (interquartile range) |
20.71 ± 17.89 16.82 (12.60-18.50) |
14.61 ± 4.88 14.64 (10.09-17.87) |
0.32 |
| GPX5 (U/g Hg), Mean ± SD Median (interquartile range) |
15.93 ± 11.64 14.72 (10.51-17.87) |
16.59 ± 7.78 15.14 (12.19-21.23) |
0.58 |
| GPX5-GPX0 (difference), Mean ± SD Median (interquartile range) |
-4.80 ± 10.06 -1.16 (-8.50 –1.25) |
2.01 ± 6.73 +1.81 (-2.50 –8.00) |
0.02 |
| MDA0 (nmol/mL), Mean ± SD Median (interquartile range) |
3.54 ± 1.85 3.40 (1.80-5.05) |
4.34 ± 2.26 3.60 (2.70-6.95) |
0.28 |
| MDA1 (nmol/mL), Mean ± SD Median (interquartile range) |
4.31 ± 2.28 3.95 (2.22-5.85) |
4.24 ± 2.39 3.65 (2.77-6.30) |
0.85 |
| MDA5 (nmol/mL), Mean ± SD Median (interquartile range) |
4.37 ± 2.41 4.0 (2.60-6.27) |
4.74 ± 1.54 4.70 (3.80-5.60) |
0.49 |
*
GPX 0: pre-transplant (baseline) glutathione peroxidase activity; GPX 5: fifth day glutathione peroxidase activity, MDA0: pretransplant malondialdehyde; MDA1: day 1 malondialdehyde; MDA5: day malondialdehyde level; NAC: N-acetylcysteine.