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. 2018 Mar 8;13(3):e0194146. doi: 10.1371/journal.pone.0194146

Fig 2. HIF1α is not the primary early transcription factor regulating gene expression in hypoxic or OGD–treated pericytes.

Fig 2

ChIP-seq data for c-JUN, NFκB, STAT3 or HIF1α were analysed for binding peaks near (5Kbp) the transcriptional binding site of genes regulated (fc>1.5, p<0.05) in hypoxic or OGD treated pericytes. Venn diagrams are for (A) 2h hypoxia, (B) 6h hypoxia, (C) 2h OGD or (D) 6h OGD-treated pericytes. The numbers of genes regulated by either of the four transcription factors (x) compared to the total number of regulated genes (y) are presented as (x/y) below each graph.