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(A) Reaction catalyzed by the 6-oxopurine PRTases. (B–D) General structures of ANPs. Single chain ANPs (B); aza-ANPs (C); and branched ANPs with an attachment at one of the first two carbons from the N9 nitrogen in the base (D). When xanthine, guanine and hypoxanthine is the base, Y = OH, Y = NH2 and Y = H, respectively.
