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| Substrate | Km (μM) | kcat (s-1) | kcat/ Km (μM-1s-1) |
|---|---|---|---|
| HGPRT-I | |||
| Guanine | 15.9 ± 4.8 | 0.38 | 0.02 |
| Hypoxanthine | 13.7 ± 2.9 | 0.26 | 0.18 |
| Xanthine | No activity detected | ||
| HGPRT-II | |||
| Guanine | 7.1±1.8 | 0.05 | 0.007 |
| Hypoxanthine | 4.2 ± 0.9 | 0.03 | 0.007 |
| Xanthine | No activity detected | ||
| HGXPRT | |||
| Guanine | 32 ± 4.8 | 1.36 | 0.04 |
| Hypoxanthine | 30.6 ± 7.8 | 2.4 | 0.08 |
| Xanthine | 31.9 ± 7.5 | 3.66 | 0.11 |
