Table 1.
Clinical characteristics of patients with idiopathic pulmonary fibrosis with acute exacerbation
| Parameters | Mean±SD |
|---|---|
| Age (years) | 74.7±11.3 |
| Gender (male/female) | (40/25) |
| Pack-year (years) | 32.4±40.6 |
| mMRC | 2.8±1.0 |
| Dyspnea duration (days) | 6.5±5.8 |
| Clubbing (%) | 29 |
| Survival time (months) | 9.6±3.0 |
| Laboratory items | |
| WBC (mm3) | 11.369.2±5368.9 |
| CRP (mg/dl) | 8.2±7.3 |
| LDH (IU/l) | 392.2±144.6 |
| KL-6 (IU/l) | 1903.4±1720 |
| ΔLDH | −5.6±115.6 |
| ΔKL-6 | 288.4±698.8 |
| Pulmonary function | |
| Percent FVC (%) | 58.2±21.2 |
| Percent DLCO (%) | 32.2±11.6 |
| pH | 7.42±0.10 |
| PaO2 (mm Hg) | 62.6±17.5 |
| PaCO2 (mm Hg) | 43.8±15.9 |
| P/F ratio(value) | 159.1±91.0 |
| Imaging findings | |
| Traction bronchiectasis | 2.3±0.7 |
| Honeycombing | 1.7±0.6 |
| GGO+consolidation | 4.8±4.2 |
| Total extent | 9.5±6.8 |
mMRC: modified Medical Research Council; WBC: white blood cell; CRP: C-reactive protein; LDH: lactate dehydrogenase; KL-6: Krebs von den Lungen-6; FVC: forced vital capacity; PaO2: partial pressure of oxygen; PaCO2: partial pressure of carbon dioxide; P/F: ratio of partial pressure of oxygen to the fraction of inspiratory oxygen; GGO: ground-glass opacity