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. Author manuscript; available in PMC: 2018 Mar 8.
Published in final edited form as: Expert Rev Clin Immunol. 2016 Jun 1;12(10):1109–1121. doi: 10.1080/1744666X.2016.1188006

Figure 1.

Figure 1

Cutaneous lupus erythematosus treatment algorithm. Treatment of mild or local disease begins with topical therapies, whereas treatment of severe or widespread disease begins with systemic therapies. If the response to therapy is inadequate, arrows indicate the direction of treatment progression. In many cases, combining therapies from multiple classes (e.g. first- and second-line systemic treatments) may be necessary.

HCQ = hydroxychloroquine; QC = quinacrine; CQ = chloroquine; MTX = methotrexate; MMF = mycophenolate mofetil