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. 2018 Feb 15;10:ecurrents.outbreaks.0bf6aeb4d30824de63c4d5d745b217f5. [Version 1] doi: 10.1371/currents.outbreaks.0bf6aeb4d30824de63c4d5d745b217f5

Supplemental Table.

Demographic and laboratory characteristics of suspected cases according to the type of infection (mono or co-infection) during the triple epidemic occurred in Campo Grande, MS, Brazil during 2016.

DENV DENV/ZIKV ZIKV
Demographic and laboratory characteristics Without WS (n=46) With WS/Severe (n=8) Without WS (n=12) With WS/Severe (n=3) (n=15)
Gender F:M 22:24 6:2 5:7 1:2 12:3
Age Median (LCL-UCL) 33 (31.1-39.8) 46.5 (31.15-39.8) 25.5 (23.4-44.1) 21 (12-71) 40 (32.6-45.26)
a Days of disease ΩMedian (LCL-UCL) 3.5 (2.5-4.4) 4.5 (0.7-11) 25.5 (23.4-44.1) 21 (12-71) 40 (32.6-45.26)
DENV-1 (n/total) 33/38 5/6 12/13 3/3 0
DENV-4 (n/total) 4/38 1/6 1/13 0/3 0
Hospitalization (%) 0 1/6 0 0/3 0
AST (IU/L)(n=total) 33 (36.6-78) (n=24) 43 (18.9-69)(n=4) 23 (24-147) (n=7) 22.5 (16-28)(n=2) 27.5 (21.4-32.5) (n=8)
ALT (IU/L)(n=total) 39.7 (37-46.4)(n=41) 62.5 (113-346)(n=4) 28 (5.8-93) (n=11) 16 (10-22.5)(n=3) 23 (17-28.1)(n=13)
Total proteins (g/dL) 7.3 (7.1-7.4)(n=40) 7.0 (6.4-7.7)(n=6) 7.3 (7.1-7.4)(n=14) 7.0 (6.4-7.7)(n=3) 7.0 (6.4-7.7)(n=15)
Albumin (g/dL) 4.05 (4.07-4.2(n=40) 4.2 (3.4-4.5)(n=6) 4.3 (4.1-4.4)(n=14) 4.1 (2.4-6.0)(n=3) 4.2 (4.05-4.4)(n=13)
Hematocrit (%) 41 (40.7-42.5)(n=46) 39.5 (33.9-43)(n=8) 43 (39-44.6)(n=14) 39 (26-53.8)(n=3) 41 (39.4-44.1)(n=15)
Platelets 103 /mm3 counts 198.5 (168-206.6) (n=46) 101 (39.4-172.1) b***(n=8) 188 (147-224) c*(n=12) 193 (40-392)(n=3) 197 (155.5-265.3) c*(n=15)
Bleeding (%) 0 6 (75%)d 1 (7.14%)b 2 (66%) 0