Table 2.
Baseline | 20% | 40% | 60% | |||||
---|---|---|---|---|---|---|---|---|
|
|
|
|
|||||
Variable | Controls | CF | Controls | CF | Controls | CF | Controls | CF |
|
|
|
|
|||||
Diameter (cm) | 0.28 ± 0.05 | 0.28 ± 0.05 | 0.28 ± 0.05 | 0.27 ± 0.05 | 0.28 ± 0.05 | 0.27 ± 0.05 | 0.28 ± 0.05 | 0.27 ± 0.05 |
Mean velocity (cm/s) | 9.3 ± 4.4 | 5.8 ± 1.4 | 8.6 ± 4.6 | 7.8 ± 2.2 | 15.3 ± 9.6* | 10.2 ± 3.7* | 18.9 ± 8.4* | 13.7 ± 4.4* |
Blood flow (ml/min) | 34.4 ± 19.1 | 21.8 ± 9.3 | 29.0 ± 13.4 | 28.0 ± 13.2 | 54.5 ± 35.4* | 36.1 ± 15.8* | 71.4 ± 38.1† | 49.4 ± 19.2† |
Retrograde blood flow (ml/min) | 2.8 ± 4.1 | 4.4 ± 6.8 | 10.3 ± 12.6‡ | 11.0 ± 9.4‡ | 12.5 ± 15.4* | 19.8 ± 15.8* | 14.3 ± 17.7* | 23.6 ± 17.1* |
Antegrade blood flow (ml/min) | 37.0 ± 20.5 | 26.3 ± 12.1 | 38.7 ± 17.6‡ | 39.8 ± 17.3‡ | 63.9 ± 32.8* | 56.0 ± 25.2* | 80.2 ± 37.7† | 73.1 ± 29.8† |
Mean shear rate (s−1) | 171 ± 54 | 277 ± 141 | 231 ± 62 | 266 ± 166 | 305 ± 131* | 458 ± 297* | 412 ± 166† | 554 ± 254† |
Heart rate (bpm) | 82 ± 10 | 76 ± 11 | 100 ± 9 | 101 ± 11 | 118 ± 16 | 127 ± 16 | 139 ± 19 | 157 ± 17# |
Values are mean ± SD.
significantly higher versus baseline and 20% intensity, independent of group (P<0.05);
significantly higher versus baseline, 20%, and 40% intensity, independent of group (P<0.05);
significantly higher versus baseline, independent of group (P<0.01);
significantly higher versus controls within same level of intensity (P=0.017).