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Effect of bortezomib on glomerular IgG deposition in SLE and control mice. A, Control and SLE mice kidney sections were stained with anti-mouse IgG FITC. Representative glomeruli are shown from three different mice in each treatment group. B, Quantification of fluorescence intensity per μm2 in each glomerulus (5 mice/group). *, p<0.05 vs. Control-vehicle. SLE mice have increased glomerular IgG staining as compared to control mice, but it is decreased after treatment with bortezomib.
