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. 2018 Mar 8;9:992. doi: 10.1038/s41467-018-03386-7

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — Lifetime of the retinal prosthesis. a Pictures of the titanium cathodes before (left column) and after (right column) bonding on the dome-shaped PDMS support. The top row is without SU-8 rigid platforms, while the bottom row is with SU-8 rigid platforms. b Picture of a KPFM measure on bonded prostheses integrating SU-8 rigid platforms. c Comparison of KPFM measures on bonded prostheses integrating SU-8 rigid platforms (99.35 ± 25.26 mV, mean ± s.d., n = 15; electrode diameter 80 µm) with respect to measures on PDMS-interface bonded to a planar glass substrate (105.50 ± 17.79 mV, mean ± s.d., n = 36; electrode diameter 100 µm). d Sketch of the accelerated ageing tests. KPFM measures have been performed at the beginning of the experiment, then prostheses have been immersed in saline solution at 87 °C and 100% humidity for 135 h, after that KPFM has been repeated, and on for four cycles. e Quantification (mean ± s.d., N = 4 prostheses, n = 4 electrodes per prosthesis) of the surface potential changes (voltage in light—voltage in dark) during accelerated ageing tests over a simulated period of 24 months (months: 0, 110.5 ± 33.53 mV; 6, 108.5 ± 33.37 mV; 12, 109.8 ± 44.59 mV; 18, 103.8 ± 25.73 mV; 24, 111.1 ± 35.48 mV)