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. 2017 Sep 8;441(1):109–124. doi: 10.1007/s11010-017-3178-7

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 9 — The effect of PKF118-310, caperatic acid and physodic acid on cell migration. a The results of the wound healing assay in DLD-1 and HCT116 cells. Relative cell migration was calculated by comparing the change in the area covered by cells immediately after the formation of a scratch and after 24 h between control cells and cells treated with the tested compounds. Mean values ± SD from two independent experiments are shown. Asterisk above bars denotes statistically significant changes, p ≤ 0.05. b The results of a transwell migration assay with HCT116 cells. The number of invading cells was assessed after fluorescent staining of the cells which migrated through the basement membrane. Mean fluorescence values (relative fluorescent units—RFU) from three experiments ± SD are shown