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. 2017 Nov 9;39(3):472–481. doi: 10.1038/aps.2017.153

Table 2. Estimated pharmacodynamic parameters of the integrated PK/PD model.

Parameters Typical estimates RES% IIV (CV%)
λ0 (h−1) 0.0065 8.9 0 FIX
λ1 (mm3·h−1) 28.1 28.6 21.1
ω0 (mm3) 42 7.1 26.3
EC50 (ng/mL) 48.5 22.1 70.1
Residual errors      
σprop (%) 10.9%    
σadd (mm3) 27.0    

RSE, relative standard error; IIV, inter-individual variability; CV, coefficient variation.