Figure 3.

Barbaloin suppressed delayed afterdepolarizations (DADs) induced by the extracellular addition of CaCl₂ in rabbit ventricular myocytes. Ten consecutive APs were recorded at a frequency of 5 Hz with a CL of 7 s. (A, B, C, D and E) show representative traces from the groups subjected to control, 3.6 mmol/L CaCl₂, 3.6 mmol/L CaCl₂ and 100 μmol/L barbaloin, 3.6 mmol/L CaCl₂ and 200 μmol/L barbaloin and wash-out treatment, respectively. F. Incidence of DADs in the control group, in the presence of 3.6 mmol/L CaCl₂ alone, after the addition of 100 μmol/L barbaloin and 200 μmol/L barbaloin and in the wash-out group (n=9. ^**P<0.01 vs control. ^##P<0.01 vs 3.6 mmol/L CaCl₂. ^&&P<0.01 vs 100 μmol/L barbaloin. ^$$P<0.01 vs 200 μmol/L barbaloin).