Table 1. Effects of barbaloin on the parameters of action potential in rabbit ventricular myocytes. n=12. *P<0.05, **P<0.01 vs control. #P<0.05, ##P<0.01 vs 100 μmol/L barbaloin.
Parameters | Control | Barbaloin (μmol/L) |
|
---|---|---|---|
100 | 200 | ||
RMP (mV) | 87±2 | 87±3 | 87±3 |
APA (mV) | 126±8 | 123±9 | 120±9 |
Vmax (V/s) | 208±12 | 199±15 | 184±17* |
APD50 (ms) | 218±10 | 196±13** | 167±10## |
APD90 (ms) | 238±13 | 215±11** | 184±13## |
RMP, resting membrane potential; APA, action potential amplitude; Vmax, maximum depolarization velocity; APD50, action potential duration at 50% completion of repolarization; APD90, action potential duration at 90% completion of repolarization.