Table 4.
Distribution of AGT alleles in mild type PE and severe PE.
| SNP | MAF | Severe PE | Mild PE | HWE | χ2 | p | aOR2 (95% CI) | Power (%) |
|---|---|---|---|---|---|---|---|---|
| M235T | T | 88 (0.35)a | 73 (0.25) | 0.56 | 3.750 | 0.053 | 1.60 (0.99–2.53) | 76.9 |
| T174M | M | 9 (0.05) | 17 (0.07) | 0.16 | 0.573 | 0.518 | 0.715 (0.29–1.71) | 29.9 |
a
Number (frequency),
b
aOR: adjusted OR, adjusted for body mass index, gestation, and baby weight.
AGT: angiotensinogen; PE: preeclampsia; SNP: single-nucleotide polymorphism; MAF: minor allele frequency; HWE: Hardy–Weinberg equilibrium; T: threonine; M: methionine; OR: odds ratio; CI: confidence interval.