Table 1.
First author, year | Participants | Duration | Liver biopsies | Noninvasive fibrosis markers | The effects of Angiotensin blockade on fibrosis | |
---|---|---|---|---|---|---|
Terui Y, 200230 | 30 patients with early stages of chronic hepatitis C | RCT | Not mentioned | Yes | Yes | Promising beneficial effects |
Rimola A, 200427 | 128 recurrent hepatitis C after LT | Retrospective cohort study | 41 months (median) | Yes | No | Beneficial effects |
Rincon D, 200537 | 123 HCV-patients who received LT | Retrospective cohort study | > 6 months | Yes | No | No beneficial effects |
Sookoian S, 200529 | 23 patients with chronic hepatitis C non-responders |
Prospective cohort study | 14 months | Yes | No | Beneficial effects |
Yoshiji H, 200538 | 20 patients with chronic hepatitis C | RCT | 12 months | No | Yes | Promising beneficial effects |
Yoshiji H, 200639 | 40 patients with chronic hepatitis C |
RCT | 12 months | No | Yes | Beneficial effects |
Debernardi-Venon W, 200740 | 47 selected cirrhotic patients | RCT | 12 months | No | Yes | Promising beneficial effects |
Corey KE, 200928 | 234 patients with hepatitis C | Retrospective cohort study | 5.08 years | Yes | No | Beneficial effects |
Colmenero J, 200941 | 14 patients with CHC with liver fibrosis | Uncontrolled open-label study | 18 months | Yes | No | Promising beneficial effects |
Cholongitas E, 201042 | 102 recurrent hepatitis C after LT | Retrospective cohort study | 13 months (median) | Yes | No | No beneficial effects |
Abu Dayyeh BK, 201132 | 192 patients with hepatitis C | RCT | 42 months | Yes | No | No beneficial effects |
Hidaka H, 201143 | 48 selected cirrhotic patients | RCT | 12 months | No | Yes | Promising beneficial effects |
Kim MY, 201244 | 85 patients with compensated alcoholic liver fibrosis | RCT | 6 months | Yes | No | Promising beneficial effects |
Yoshiji H, 201231 | 110 patients with cirrhosis associated with hepatocellular carcinoma | RCT | 48 months | No | Yes | Beneficial effects |
Guillaud O, 201345 | 109 recurrent hepatitis C after LT | Retrospective cohort study | 23 months (median) | Yes | No | No beneficial effects |
RCT, randomized controlled trial; LT, liver transplantation.