Table 2.
Plasma Ang-II, Ang-(1–7), ratio of Ang-II/Ang-(1–7) and TNF-α levels in three groups.
| Groups | Normal (n = 13) |
Noncritical CAD (n = 17) |
Critical CAD (n = 82) |
p value |
|---|---|---|---|---|
| Ang-II (pg/ml) | 25.1 ± 5.2 | 23.3 ± 4.8 | 32.7 ± 8.3 | 0.000 |
| Ang-(1–7) (pg/ml) | 21.0 ± 4.1 | 20.1 ± 4.5 | 24.1 ± 5.1 | 0.004 |
| Ang-II/Ang-(1–7) | 1.19 ± 0.08 | 1.17 ± 0.11 | 1.38 ± 0.30 | 0.006 |
| TNF-α | 145 ± 63 | 163 ± 43 | 233 ± 77 | 0.000 |
Ang-II: angiotensin II; Ang-(1–7): angiotensin-(1–7); TNF-α: tumor necrosis factor-α; CAD: coronary artery disease.