Table 2.

Blood pressure and hypertension status at baseline as reported in the six included trials (values are mean (SD)).

Study	n	Baseline SBP		Baseline DBP		Baseline MAP		Hypertensive subjects (%)		Hypertension threshold (SD)
		Active	Placebo	Active	Placebo	Active	Placebo	Active	Placebo	mm Hg
		mm Hg	mm Hg	mm Hg	mm Hg	mm Hg	mm Hg
Ravid et al.16	156					98 ± 4 (84–105)	96 ± 4 (84–104)	0	0	140/90 (MAP 107)
ROADMAP5	4299	137 ± 16	136 ± 15	81 ± 10	80 ± 9			51	48	135/80
ADVANCE18	7986	145 ± 22	145 ± 21	81 ± 11	81 ± 11			68	69	140/90
DIRECT 24	1607	123 ± 9	123 ± 9	75 ± 6	76 ± 7			62	62	130/85
BENEDICT3	601	151 ± 15	152 ± 15	87 ± 8	88 ± 7	109 ± 9	109 ± 9	100	100	130/85
MICROHOPEa,17	2272	142 ± 20	142 ± 20	80 ± 11	79 ± 11			58	54	160/90

BP: blood pressure; DBP: diastolic blood pressure; MAP: mean arterial pressure; SBP: systolic blood pressure; SD: standard deviation.

^aMean BP values from full study population including approximately 30% with baseline microalbuminuria.