Table 1.
Group | n | Heart rate (bpm) |
Systolic blood pressure (mmHg) |
Diastolic blood pressure (mmHg) |
||||||
---|---|---|---|---|---|---|---|---|---|---|
T 0 | T 100 | ΔT (T100 − T0) | T 0 | T 100 | ΔT (T100 − T0) | T 0 | T 100 | ΔT (T100 − T0) | ||
Veh | 6 | 424 ± 17 | 418 ± 15 | −6 | 143 ± 8 | 137 ± 7 | −6 | 112 ± 6 | 102 ± 6 | −10 |
Quin | 6 | 433 ± 14 | 393 ± 11Δ | −40 | 123 ± 5* | 113 ± 7* | −10 | 98 ± 4* | 88 ± 4* | −10 |
Pro | 5 | 419 ± 19 | 400 ± 27 | −19 | 148 ± 5 | 118 ± 7Δ | −30 | 110 ± 5 | 90 ± 6Δ | −20 |
Quin+Pro | 5 | 419 ± 23 | 409 ± 5 | −10 | 128 ± 9* | 104 ± 8*Δ | −24 | 99 ± 4* | 78 ± 3Δ* | −21 |
Veh – control with lipofundin infusion, Quin – rats treated with quinapril and lipofundin infusion, Pro – control with propofol infusion, Quin+Pro – rats treated with quinapril and propofol infusion,T0 – beginning of the experiment, T100 – end of the experiment, after 100 min flow registration. Data are expressed as mean ± SEM *p < 0.05 vs Veh; Δp < 0.05 T100 vs T0.