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. 2016 Dec 12;17(4):1470320316668435. doi: 10.1177/1470320316668435

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© The Author(s) 2016

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 3. — Comparisons of serum ACE activities and serum ACE concentrations between heart failure cohorts.

Serum ACE activity (panel (a)) and ACE concentration (panel (b)) were measured in hypertensive patients with heart failure with reduced ejection fraction (HFrEF, n=102), hypertensive patients with heart failure with preserved ejection fraction (HFpEF, n=47) and patients with HFrEF without hypertension (n=39). Statistical analyses of biochemical measurements were performed by one-way analysis of variance (ANOVA) followed by nonparametric Kruskal–Wallis test among groups. Bars represent mean ± SEM. Correlation was considered to be significant when p<0.05. Lack of statistical difference is labelled by NS.