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. 2016 Dec 12;17(4):1470320316668435. doi: 10.1177/1470320316668435

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© The Author(s) 2016

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 7. — Comparison of the prognostic value for serum ACE2 activity and amino-terminal pro-B-type natriuretic peptide (NT-proBNP) concentration to differentiate HFrEF and HFpEF from hypertension.

Receiver operating characteristic (ROC) curves were generated to test the diagnostic value of serum ACE2 activity (panels (a) and (b)) or NT-proBNP (panels (c) and (d)) to differentiate between patients with heart failure and hypertension without heart failure. Results for HFrEF vs. hypertensive are shown on panels (a) and (c), results for HFpEF vs. hypertensive are shown on panels (b) and (d). Parameters of the ROC analysis are shown as inserts in the plots.