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. 2016 Dec 12;17(4):1470320316668435. doi: 10.1177/1470320316668435

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© The Author(s) 2016

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 8. — Effects of comorbidities on serum ACE2 activity in cardiovascular patients.

The effects of comorbidities such as dyslipidemia (panel (a)), atrial fibrillation (AF, panel (b)), diabetes (panel (c)) and gender (panel (d)) are shown in cardiovascular patients (healthy, hypertensive without heart failure, heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF)). Statistical differences between patient groups with and without of the defined comorbidity are indicated: asterisks represent statistically significant differences, NS represents no significant statistical difference. Statistical analysis was made by a nonparametric test (Kruskal–Wallis).