Table 2.
Changes to study parameters after nephrectomy compared to predonation levels (n=16).
| Parameter | Preoperative | Postoperative 15th day | Postoperative 1st month | Postoperative 6th month | Postoperative 1st year | P value |
|---|---|---|---|---|---|---|
| Cre (mg/dl) (mean ± SD) | 0.73±0.14 | 1.09±0.25*** | 1.09±0.26*** | 1.01±0.2*** | 1.06±0.2*** | ***P<0.001 |
| eGFR (ml/min/1.73 m²) (mean ± SD) | 98±15 | 68±18*** | 67±20*** | 72±17*** | 68±16*** | ***P<0.001 |
| Uric acid (mg/dl) (mean ± SD) | 4.5±1.1 | 4.2±1.2** | 5.0±1.3*** | 4.9±1.2*** | 5±1.3*** |
**P<0.01 ***P<0.001 |
| UPCR (g/g) (mean ± SD) | 0.06±0.01 | 0.09±0.04** | 0.08±0.04* | 0.09±0.08# | 0.06±0.02# |
*P<0.05 **P<0.01 #P>0.05 |
| Office SBP (mmHg) (mean ± SD) | 112±13 | 119±11# | 113±7# | 114±17# | 110±9# | #P>0.05 |
| Office DBP (mmHg) (mean ± SD) | 73±8 | 77±9# | 78±6# | 76±9# | 72±6# | #P>0.05 |
| uAGT/cre (µg/g) (median ± SE) | 4.75±0.70 | 17.4±4.9** | 28.8±6.58** | 36.1±8.3** | 23.9±7.7* |
*P<0.05 **P<0.01 |
| uAGT/pro (µg/g) (median ± SE) | 77±13 | 187±38** | 312±47*** | 450±65*** | 300±62** |
**P<0.01 ***P<0.001 |
| cRV (cm3/m²) (mean ± SD) | 122±22 | 151±31*** | 169±29*** | ***P<0.001 |
Cre: creatinine; Pro: protein; eGFR: estimated glomerular filtration rate; UPCR: urinary protein/creatinine ratio; SBP: systolic blood pressure; DBP: diastolic blood pressure; uAGT: urinary angiotensinogen, cRV: corrected renal volume (renal volume/body surface area).
*
/**/***/#P values are given by comparing the parameter to the baseline value.