Skip to main content
. 2018 Jan 17;15(4):4423–4426. doi: 10.3892/ol.2018.7817

Figure 2.

Figure 2.

Effect of EA on EGFR activation in lipid rafts. (A) Effect of EA on cholesterol content in total membrane or detergent-resistant raft fractions.*P<0.001 vs. 0 group. (B) EGFR and phosphorylated EGFR levels in lipid rafts or membrane fractions in CT26 cells. (C) Effect of MbCD on EA-induced EGFR phosphorylation. (D) Effect of MbCD on EA-induced ERK1/2 and p38 phosphorylation in CT26 cells. Tubulin was used as an internal control. Each bar or point represents mean ± SD of three independent experiments. EA, elaidic acid; EGFR, epidermal growth factor receptor; MbCD, methyl-β-cyclodextrin; pERK1/2, phosphorylated ERK1/2; pp38, phosphorylated p38.