Figure 3.

Effect of EA, with or without SIM, on stemness and energy metabolism. (A) Protein expression levels of nanog, c-Myc, and PGC-1A in HT29 cells treated with EA or EA and MbCD. Tubulin was used as an internal control. (B) Effect of simvastatin on tumor growth of HT29 subcutaneous tumors in nude mice treated with EA. SIM (20 mg/kg/day) was administrated with a gavage for 10 days after the inoculation. Error bars are the mean ± SD. EA, elaidic acid; SIM, simvastatin; PGC-1A, proliferator-activated receptor γ coactivator-1α.