Table II.
Correlation between MED15 expression and hepatocellular carcinoma clinicopathological features in the GSE14520 cohort.
MED15 expression, n | ||||
---|---|---|---|---|
Variable | Total, n | High | Low | P-value |
Sex | 241 | 0.756 | ||
Male | 210 | 148 | 62 | |
Female | 31 | 21 | 10 | |
Age (years) | 241 | 0.768 | ||
≤50 | 124 | 88 | 36 | |
>50 | 117 | 81 | 36 | |
No. of tumors | 241 | 0.455 | ||
Solitary | 189 | 129 | 60 | |
Multiple | 52 | 40 | 12 | |
Tumor size (cm) | 241 | 0.033a | ||
≤5 | 153 | 100 | 53 | |
>5 | 88 | 69 | 19 | |
BCLC staging | 217 | 0.031a | ||
A | 152 | 102 | 50 | |
B + C | 65 | 53 | 12 | |
TNM staging | 225 | 0.127 | ||
I | 96 | 60 | 36 | |
II + III | 129 | 93 | 36 | |
AFP level (ng/ml) | 237 | 0.002a | ||
≤300 | 128 | 78 | 50 | |
>300 | 109 | 87 | 22 | |
Cirrhosis | 241 | 0.225 | ||
Yes | 222 | 158 | 64 | |
No | 19 | 11 | 8 | |
Metastasis risk | 241 | 0.001a | ||
Low | 121 | 73 | 48 | |
High | 120 | 96 | 24 | |
Relapse | 241 | 0.303 | ||
Yes | 136 | 99 | 37 | |
No | 105 | 70 | 35 |
Value indicates a statistically significant difference. MED15, mediator complex subunit 15; AFP, α-fetoprotein; BCLC, Barcelona Clinic Liver Cancer.