Table I.

miRNA microarray analyses of differentially expressed miRNAs in OS tissues and adjacent normal tissues (OS tissues/normal tissues).

miRNAs	Fold-change	P-value
Upregulated
hsa-miR-351-3p	20.18	0.0107
hsa-miR-202-3p	19.04	0.0178
hsa-miR-273-3p	17.95	0.0117
hsa-miR-121-5p	16.77	0.0275
hsa-miR-208-3p	16.39	0.0208
hsa-miR-248	15.28	0.0099
hsa-miR-128-5p	14.73	0.0047
hsa-miR-19-3p	14.07	0.0137
hsa-miR-213	13.78	0.0472
hsa-miR-192	13.07	0.0429
hsa-miR-191	12.18	0.0378
hsa-miR-576-3p	11.45	0.0118
hsa-miR-472-3p	10.11	0.0251
hsa-miR-502a-3p	9.19	0.0187
hsa-miR-521-3p	8.37	0.0049
hsa-miR-541e	8.01	0.0391
hsa-miR-131-5p	6.89	0.0172
hsa-miR-9a-5p	6.12	0.0394
hsa-miR-493-3p	5.99	0.0187
hsa-miR-702-5p	5.08	0.0292
hsa-miR-198	4.77	0.0031
hsa-miR-130	4.54	0.0093
hsa-miR-122-5p	3.93	0.0172
hsa-miR-122	3.01	0.0364
hsa-miR-174	2.91	0.0208
hsa-miR-215	2.66	0.0407
hsa-miR-274	2.27	0.0099
hsa-miR-176	2.11	0.0152
hsa-miR-18	1.93	0.0381
Downregulated
hsa-miR-197-3p	0.99	0.0113
hsa-miR-415-5p	0.97	0.0309
hsa-miR-1406	0.87	0.0293
hsa-miR-13a-5p	0.82	0.0183
hsa-miR-311a	0.78	0.0211
hsa-miR-307b	0.72	0.0191
hsa-miR-51-5p	0.69	0.0313
hsa-miR-25b-5p	0.62	0.0091
hsa-miR-25a-5p	0.59	0.0049
hsa-miR-99a-3p	0.53	0.0412
hsa-miR-110	0.51	0.0279
hsa-miR-238-3p	0.45	0.0019
hsa-miR-47-5p	0.44	0.0373
hsa-miR-29-3p	0.42	0.0147
hsa-miR-37-5p	0.39	0.0045
hsa-miR-215	0.37	0.0078
hsa-miR-27-3p	0.35	0.0128
hsa-miR-90	0.29	0.0327
hsa-miR-77-5p	0.27	0.0401
hsa-miR-398	0.16	0.0019
hsa-miR-187	0.11	0.0108
hsa-miR-150	0.09	0.0071
hsa-miR-381-3p	0.07	0.0131
hsa-miR-294	0.06	0.0307
hsa-miR-201-5p	0.05	0.0287
hsa-miR-499a-5p	0.04	0.0175

miRNA, microRNA; OC, osteosarcoma.