Proliferative ability of (A and B) ACHN and (C and D) 786-O cells transfected with (A and C) miR-216a-5p mimic or NC and (B and D) miR-216a-5p inhibitor or inhibitor NC were assessed by CCK-8. *P<0.05, **P<0.01, ***P<0.001. NC, negative control; OD, optical density; CCK-8, Cell Counting kit 8.