. Author manuscript; available in PMC: 2018 Mar 10.

Published in final edited form as: Nat Genet. 2017 Sep 4;49(10):1450–1457. doi: 10.1038/ng.3943

Table 2.

Enrichment in directional consistency for all SNPs in T2D and CHD association scan

			T2D and CHD in meta-analyses
p-value cut point		# of SNPs in total	# of SNPs CHD/T2D consistent	% of SNPs CHD/T2D consistent	adjusted −log₁₀(p-value)^*
T2D	CHD	# of SNPs in total	# of SNPs CHD/T2D consistent	% of SNPs CHD/T2D consistent	adjusted −log₁₀(p-value)^*
(0, 5×10⁻⁸]	–	1,260	959	76.11%	76.966
–	(0, 5×10⁻⁸]	595	287	48.24%	0.062
(0.5, 1]	(0.5, 1]	1,874,138	948,292	50.60%	–
(5×10⁻⁸, 0.05]	(5×10⁻⁸, 0.05]	36,242	29,634	81.77%	3319.168

P-value values from the binomial sign test were reported. The probability used to estimate the p-values in the binomial sign test is the percentage highlighted in red.