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. Author manuscript; available in PMC: 2018 Mar 9.
Published in final edited form as: J Med Chem. 2016 Jul 22;59(15):7075–7088. doi: 10.1021/acs.jmedchem.5b02038

Figure 7.

Figure 7

3D scatter plot of the top three image features correlated to antischistosomal activity of the investigated compounds on female S. mansoni worms after 48 h drug exposure. Each point in the graph represents a well/condition in the assay. Sample images are shown for selected wells to illustrate the different phenotypes captured by these three parameters (OA, object area; MS, mobility score; PI, pixel intensity of the worm object). The green outlines represent the position of each parasite over five time points (3 s interval) overlaid on the initial position (red outline).