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. 2018 Mar 6;6:e4466. doi: 10.7717/peerj.4466

Table 2. Novel A-to-G(I) mRNA-recoding sites.

Sitea Gene Amino acid change Tissue(s)b Median editing ratioc Nd
4:57,110,146 IGFBP7 E69G AOR, MAM 0.11 197
7:38,262,191 TARP N58S BLO 0.40 37
8:144,247,668 MROH1 S1037G, S1028G LIV, VAF 0.47 94
9:33,271,197 CHMP5 K121E BLO, SUF 0.07 853
10:45,789,442 FAM21C K1158R,
K1124R,
K1199R
BLO, LIV, SUF,
SKM, VAF
0.50 216
12:57,625,434 SLC26A10 R500G MAM 0.29 74
16:30,188,879 CORO1A E434G VAF 0.17 22
17:1,534,142 PITPNA D242G LIV 0.08 55
19:7,520,407 ZNF358 S389G MAM 0.09 95
19:54,221,229 LILRB3 Q270R FOC, MAC 0.21 251
19:54,221,256 LILRB3 E261G FOC, MAC 0.50 223

Notes.

a

Genomic coordinate of the site (GRCh38). Given as chromosome:position.

b

Tissue abbreviations: aortic wall (AOR), internal mammary artery (MAM), whole blood (BLO), liver (LIV), visceral fat (VAF), subcutaneous fat (SUF), skeletal muscle (SKM), foam cells (FOC), and macrophages (MAC).

c

Across all samples.

d

Number of samples in which editing was found. This number may include samples whose editing signal was lower than required to meet the criteria for detection.