Table 2. Novel A-to-G(I) mRNA-recoding sites.
| Sitea | Gene | Amino acid change | Tissue(s)b | Median editing ratioc | Nd |
|---|---|---|---|---|---|
| 4:57,110,146 | IGFBP7 | E69G | AOR, MAM | 0.11 | 197 |
| 7:38,262,191 | TARP | N58S | BLO | 0.40 | 37 |
| 8:144,247,668 | MROH1 | S1037G, S1028G | LIV, VAF | 0.47 | 94 |
| 9:33,271,197 | CHMP5 | K121E | BLO, SUF | 0.07 | 853 |
| 10:45,789,442 | FAM21C | K1158R, K1124R, K1199R |
BLO, LIV, SUF, SKM, VAF |
0.50 | 216 |
| 12:57,625,434 | SLC26A10 | R500G | MAM | 0.29 | 74 |
| 16:30,188,879 | CORO1A | E434G | VAF | 0.17 | 22 |
| 17:1,534,142 | PITPNA | D242G | LIV | 0.08 | 55 |
| 19:7,520,407 | ZNF358 | S389G | MAM | 0.09 | 95 |
| 19:54,221,229 | LILRB3 | Q270R | FOC, MAC | 0.21 | 251 |
| 19:54,221,256 | LILRB3 | E261G | FOC, MAC | 0.50 | 223 |
Notes.
Genomic coordinate of the site (GRCh38). Given as chromosome:position.
Tissue abbreviations: aortic wall (AOR), internal mammary artery (MAM), whole blood (BLO), liver (LIV), visceral fat (VAF), subcutaneous fat (SUF), skeletal muscle (SKM), foam cells (FOC), and macrophages (MAC).
Across all samples.
Number of samples in which editing was found. This number may include samples whose editing signal was lower than required to meet the criteria for detection.