TABLE 3.
Multivariate model of factors predicting mastectomy
| OR | p value | 95 % CI | |
|---|---|---|---|
| Subtype | |||
| HER2-positive/HR-positive | 1.31 | <0.001 | 1.24–1.38 |
| HER2-positive/HR-negative | 1.73 | <0.001 | 1.60–1.87 |
| HER2-negative/HR-positive | Ref | ||
| TNBC | 1.05 | 0.057 | 1.00–1.10 |
| Age (years) | |||
| <40 | 2.37 | <0.001 | 2.19–2.56 |
| 40–49 | 1.38 | <0.001 | 1.32–1.45 |
| 50–59 | Ref | ||
| 60–69 | 0.83 | <0.001 | 0.79–0.87 |
| 70–79 | 0.86 | <0.001 | 0.82–0.91 |
| ≥80 | 0.93 | 0.034 | 0.88–0.99 |
| Stage | |||
| I | Ref | ||
| II | 2.31 | <0.001 | 2.24–2.39 |
| III | 8.17 | <0.001 | 7.73–8.63 |
| Marital status | |||
| Married | Ref | ||
| Single | 0.94 | 0.005 | 0.89–0.98 |
| Separated | 1.02 | 0.259 | 0.98–1.06 |
| Race | |||
| White | Ref | ||
| Black | 0.91 | 0.001 | 0.87–0.96 |
| Other | 1.18 | <0.001 | 1.12–1.25 |
| Hispanic | |||
| No | Ref | ||
| Yes | 1.05 | 0.072 | 1.00–1.11 |
| Year of diagnosis | |||
| 2010 | Ref | ||
| 2011 | 0.96 | 0.012 | 0.93–0.99 |
OR odds ratio, CI confidence interval, HER2 human epidermal growth factor receptor-2, HR hormone receptor, TNBC triple-negative breast cancer