Fig 2.

(A) MET-GAB1 proximity ligation assay (PLA) analysis of formalin-fixed, paraffin-embedded samples from the HLA-DRB1-MET patient, two different MET exon 14 (ex14) skipping–positive patients, and an ALK rearrangement–positive patient (negative control). Scale bar is 50 microns. (B) Quantification of PLA analysis displayed as the average number of dots per nucleus. Data are expressed as means ± SEM. The HLA-DRB1-MET sample displayed a significantly higher PLA score than did the ALK sample, as determined by analysis of variance followed by Bonferroni’s post hoc analysis. (*) P < .001.